Patent · US Active

Anthracycline derivative conjugates, process for their preparation and their use as antitumor compounds

US9695240B2 · kind B2 · utility

8Cited by

10References

9Claims

0Family size

Assignees

Genentech, Inc. · US
NERVIANO MEDICAL SCIENCES S.R.L. · IT

Inventors

Italo Beria · Nerviano, IT
Michele Caruso · Milano, IT
John A. Flygare · Burlingame, US
Vittoria Lupi · Milano, IT
Rita Perego · Milano, IT
Paul Polakis · Mill Valley, US
Andrew Polson · San Francisco, US
Matteo Salsa · Novara, IT
Susan D. Spencer · Tiburon, US
Barbara Valsasina · Milano, IT
Robert L. Cohen · San Mateo, US

Key dates

Filing date	Oct 30, 2014
Grant date	Jul 4, 2017
Priority date	—
Expiry date	Feb 24, 2035

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K2317/76
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention relates to conjugates of therapeutically useful anthracyclines with carriers such as polyclonal and monoclonal antibodies, proteins or peptides of natural or synthetic origin; methods for their preparation, pharmaceutical composition containing them and use thereof in treating certain mammalian tumors.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.