Inventor · Natick, MA, US

Edward R. Lee

30Patents
15h-index
44Co-inventors
81Inventor score

Filing activity: Dec 9, 1994 → Aug 24, 2017

Most-cited inventions

PatentTitleAreaCited byStatus
US5948767A Cationic amphiphile/DNA complexes Chemistry; Metallurgy 146 Expired
US5767099A Cationic amphiphiles containing amino acid or dervatized amino acid groups for intracellular delivery of therapeutic molecules Emerging Cross-Sectional Technologies 117 Expired
US5719131A Cationic amphiphiles containing dialkylamine lipophilic groups for intracellular delivery of therapeutic molecules Emerging Cross-Sectional Technologies 69 Expired
US5935936A Compositions comprising cationic amphiphiles and co-lipids for intracellular delivery of therapeutic molecules Chemistry; Metallurgy 55 Expired
US5650096A Cationic amphiphiles for intracellular delivery of therapeutic molecules Chemistry; Metallurgy 52 Expired
US5783565A Cationic amphiphiles containing spermine or spermidine cationic group for intracellular delivery of therapeutic molecules Emerging Cross-Sectional Technologies 49 Expired
US6071890A Organ-specific targeting of cationic amphiphile/DNA complexes for gene therapy Chemistry; Metallurgy 37 Expired
US5925628A Cationic amphiphiles for intracellular delivery of therapeutic molecules Chemistry; Metallurgy 35 Expired
US5840710A Cationic amphiphiles containing ester or ether-linked lipophilic groups for intracellular delivery of therapeutic molecules Emerging Cross-Sectional Technologies 32 Expired
US5948925A Cationic amphiphiles containing linkers derived from neutral or positively charged amino acids Chemistry; Metallurgy 32 Expired
US5747471A Cationic amphiphiles containing steroid lipophilic groups for intracellular delivery of therapeutic molecules Chemistry; Metallurgy 19 Expired
US6383814B1 Cationic amphiphiles for intracellular delivery of therapeutic molecules Chemistry; Metallurgy 18 Expired
US5939401A Cationic amphiphile compositions for intracellular delivery of therapeutic molecules Human Necessities 17 Expired
US5910487A Cationic amphiphiles and plasmids for intracellular delivery of therapeutic molecules Chemistry; Metallurgy 15 Expired
US5942634A Cationic amphiphiles for cell transfections Chemistry; Metallurgy 15 Expired
US8304447B2 2-acylaminopropoanol-type glucosylceramide synthase inhibitors Chemistry; Metallurgy 14 Active
US5912239A Imidazole-containing cationic amphiphiles for intracellular delivery of therapeutic molecules Chemistry; Metallurgy 13 Expired
US8309593B2 2-acylaminopropoanol-type glucosylceramide synthase inhibitors Chemistry; Metallurgy 11 Active
US8940776B2 2-acylaminopropoanol-type glucosylceramide synthase inhibitors Chemistry; Metallurgy 8 Active
US9272996B2 2-acylaminopropoanol-type glucosylceramide synthase inhibitors Chemistry; Metallurgy 6 Active
US9556214B2 Compounds, compositions, and methods for the treatment of cancers Emerging Cross-Sectional Technologies 5 Active
US9745294B2 2-acylaminopropoanol-type glucosylceramide synthase inhibitors Chemistry; Metallurgy 2 Active
US6323191A Small molecule chloride transport Human Necessities 2 Expired
US6331524A Organ-specific targeting of cationic amphiphile / DNA complexes for gene therapy Chemistry; Metallurgy 1 Expired
US5952516A Cationic amphiphiles containing multiplesteroid lipophilic groups Chemistry; Metallurgy 1 Expired

Source: USPTO / EPO open patent data. Inventor disambiguation is heuristic; counts are objective bibliographic measures.