Inventor · New York, NY, US

Michel Sadelain

37Patents
7h-index
38Co-inventors
69Inventor score

Filing activity: Sep 18, 1998 → Jun 13, 2023

Most-cited inventions

PatentTitleAreaCited byStatus
US7446190B2 Nucleic acids encoding chimeric T cell receptors Chemistry; Metallurgy 369 Expired
US8389282B2 Constitutive expression of costimulatory ligands on adoptively transferred T lymphocytes Emerging Cross-Sectional Technologies 208 Active
US6451995B1 Single chain FV polynucleotide or peptide constructs of anti-ganglioside GD2 antibodies, cells expressing same and related methods Chemistry; Metallurgy 89 Expired
US9220728B2 Constitutive expression of costimulatory ligands on adoptively transferred T lymphocytes Emerging Cross-Sectional Technologies 36 Active
US10370452B2 Effective generation of tumor-targeted T cells derived from pluripotent stem cells Chemistry; Metallurgy 14 Active
US10117897B2 Constitutive expression of costimulatory ligands on adoptively transferred T lymphocytes Emerging Cross-Sectional Technologies 10 Active
US10654928B2 Compositions and methods for immunotherapy Chemistry; Metallurgy 9 Active
US11267901B2 Compositions and methods for immunotherapy Chemistry; Metallurgy 7 Active
US11242375B2 Immune cell compositions and methods of use Chemistry; Metallurgy 5 Active
US6642043B1 Double mutants of dihydrofolate reductase and methods of using same Chemistry; Metallurgy 5 Expired
US10350243B2 Methods for off-the-shelf-tumor immunotherapy using allogeneic T-cell precursors Chemistry; Metallurgy 3 Active
US7541179B2 Vector encoding human globin gene and use thereof in treatment of hemoglobinopathies Chemistry; Metallurgy 3 Expired
US11229669B2 Cells comprising non-HLA restricted T cell receptors Chemistry; Metallurgy 3 Active
US11932690B2 Enhanced chimeric antigen receptors and uses thereof Chemistry; Metallurgy 2 Active
US11377637B2 Transgenic T cell and chimeric antigen receptor T cell compositions and related methods Emerging Cross-Sectional Technologies 2 Active
US8058061B2 Vector encoding human globin gene and use thereof in treatment of hemoglobinopathies Chemistry; Metallurgy 2 Active
US10633441B2 Mesothelin-targeted chimeric antigen receptors and uses thereof Chemistry; Metallurgy 1 Active
US11702472B2 Method of reducing mesothelin-expressing tumor burden by administration of T cells comprising mesothelin-targeted chimeric antigen receptors Chemistry; Metallurgy 0 Active
US12263220B2 Compositions and methods for immunotherapy Chemistry; Metallurgy 0 Active
US12018077B2 Methods of treatments using antigen-binding proteins targeting CD56 Chemistry; Metallurgy 0 Active
US10538588B2 Mesothelin-targeted chimeric antigen receptors and methods of making them Chemistry; Metallurgy 0 Active
US11717579B2 Globin gene therapy for treating hemoglobinopathies Chemistry; Metallurgy 0 Active
US12331129B2 Chimeric receptors targeting ADGRE2 and/or CLEC12A and uses thereof Chemistry; Metallurgy 0 Active
US12036244B2 Cells comprising non-HLA restricted T cell receptors Chemistry; Metallurgy 0 Active
US10059923B2 Methods for off-the-shelf tumor immunotherapy using allogeneic T-cell precursors Chemistry; Metallurgy 0 Active

Source: USPTO / EPO open patent data. Inventor disambiguation is heuristic; counts are objective bibliographic measures.