Inventor · Holden, MA, US

Terence Flotte

23Patents
13h-index
30Co-inventors
81Inventor score

Filing activity: Jun 2, 1992 → Jan 14, 2022

Most-cited inventions

PatentTitleAreaCited byStatus
US5658776A Generation of high titers of recombinant AAV vectors Chemistry; Metallurgy 193 Expired
US7094604B2 Production of pseudotyped recombinant AAV virions Chemistry; Metallurgy 112 Expired
US8734809B2 AAV's and uses thereof Chemistry; Metallurgy 96 Active
US5587308A Modified adeno-associated virus vector capable of expression from a novel promoter Chemistry; Metallurgy 83 Expired
US5866696A Modified adeno-associated virus vector capable of expression from a novel promoter Chemistry; Metallurgy 61 Expired
US5989540A Modified adeno-associated virus vector capable of expression from a novel promoter Chemistry; Metallurgy 51 Expired
US9284357B2 AAV's and uses thereof Chemistry; Metallurgy 45 Active
US9226976B2 RAAV-based compositions and methods for treating alpha-1 anti-trypsin deficiencies Chemistry; Metallurgy 32 Active
US9885057B2 RAAV-based compositions and methods for treating alpha-1 anti-trypsin deficiencies Chemistry; Metallurgy 20 Active
US5990279A Amino-terminally truncated cystic fibrosis transmembrane conductance regulator Chemistry; Metallurgy 17 Expired
US10077452B2 rAAV-based compositions and methods Chemistry; Metallurgy 17 Active
US6165781A Modified adeno-associated virus vector capable of expression from a novel promoter Chemistry; Metallurgy 17 Expired
US10035825B2 AAV's and uses thereof Chemistry; Metallurgy 16 Active
US10597656B2 RAAV-based compositions and methods Chemistry; Metallurgy 11 Active
US10689420B2 AAV's and uses thereof Chemistry; Metallurgy 8 Active
US6461606B1 Materials and methods for gene therapy Chemistry; Metallurgy 7 Expired
US10480011B2 Recombinant AAV variants and uses thereof Chemistry; Metallurgy 6 Active
US8137962B2 Compositions for treating cystic fibrosis Chemistry; Metallurgy 1 Active
US11254939B2 RAAV-based compositions and methods Chemistry; Metallurgy 1 Active
US11542525B2 Recombinant AAV variants and uses thereof Chemistry; Metallurgy 1 Active
US11920133B2 RAAV-based compositions and methods Chemistry; Metallurgy 0 Active
US11834474B2 AAV's and uses thereof Chemistry; Metallurgy 0 Active
US11884926B2 Campaign-ready series of recombinant adeno-associated virus (rAAV) complementing plasmids Chemistry; Metallurgy 0 Active

Source: USPTO / EPO open patent data. Inventor disambiguation is heuristic; counts are objective bibliographic measures.