Inventor · Toronto, ON, CA

Methvin Isaac

36Patents
8h-index
78Co-inventors
78Inventor score

Filing activity: Jun 29, 1999 → May 6, 2022

Most-cited inventions

PatentTitleAreaCited byStatus
US6660753B2 Heteropolycyclic compounds and their use as metabotropic glutamate receptor antagonists Chemistry; Metallurgy 115 Expired
US7112595B2 Heteropolycyclic compounds and their use as metabotropic glutamate receptor antagonists Chemistry; Metallurgy 63 Expired
US7485722B2 Spiro-oxazolidinone compounds and their use as metabotropic glutamate receptor potentiators Chemistry; Metallurgy 28 Active
US7585881B2 Additional heteropolycyclic compounds and their use as metabotropic glutamate receptor antagonists Chemistry; Metallurgy 24 Active
US7074809B2 Compounds Chemistry; Metallurgy 18 Expired
US7960422B2 Pharmaceutically active compounds containing tetrazolyl and triazolyl rings Chemistry; Metallurgy 9 Active
US6166072A Amino acid derivatives Chemistry; Metallurgy 8 Expired
US7868008B2 Substituted isoindolones and their use as metabotropic glutamate receptor potentiators Chemistry; Metallurgy 8 Expired
US6380242B1 N-alkylamino-indoles for the treatment of migraine Human Necessities 7 Expired
US7456200B2 Compounds Chemistry; Metallurgy 5 Expired
US7968570B2 Isoindolone compounds and their use as metabotropic glutamate receptor potentiators Chemistry; Metallurgy 4 Active
US7799792B2 Metabotropic glutamate receptor oxadiazole ligands and their use as potentiators 841 Chemistry; Metallurgy 4 Active
US6103743A Unsaturated amino acid derivatives Chemistry; Metallurgy 4 Expired
US6716837B1 Heterocyclic compounds for the treatment of migraine Chemistry; Metallurgy 3 Expired
US8377940B2 Oxadiazole derivatives and their use as metabotropic glutamate receptor potentiators—842 Chemistry; Metallurgy 3 Active
US7476684B2 Compounds for the treatment of neurological, psychiatric or pain disorders Human Necessities 3 Active
US6897215B1 Compounds having 5-HT6 receptor antagonist activity Chemistry; Metallurgy 2 Expired
US11518764B2 Substituted heteroaryls as inhibitors of the BCL6 BTB domain protein-protein interaction Human Necessities 2 Active
US7807706B2 Metabotropic glutamate-receptor-potentiating isoindolones Chemistry; Metallurgy 2 Expired
US11174250B2 Substituted carboxamides as inhibitors of WDR5 protein-protein binding Chemistry; Metallurgy 2 Active
US11505539B2 Deuterated compounds as inhibitors of the BCL6 BTB domain protein-protein interaction and/or as BCL6 degraders Chemistry; Metallurgy 2 Active
US7678796B2 MGluR5 modulators I Chemistry; Metallurgy 1 Active
US11319299B2 Substituted carboxamides as inhibitors of WDR5 protein-protein binding Human Necessities 1 Active
US7576077B2 Fused heterocyclic compounds and their use as metabotropic glutamate receptor antagonists Chemistry; Metallurgy 1 Expired
US11242351B2 Tricyclic inhibitors of the BCL6 BTB domain protein-protein interaction and uses thereof Chemistry; Metallurgy 0 Active

Source: USPTO / EPO open patent data. Inventor disambiguation is heuristic; counts are objective bibliographic measures.