Inventor · Bethesda, MD, US

Stephen H. Leppla

37Patents
5h-index
41Co-inventors
69Inventor score

Filing activity: Feb 12, 1993 → Jan 20, 2017

Most-cited inventions

PatentTitleAreaCited byStatus
US5677274A Anthrax toxin fusion proteins and related methods Chemistry; Metallurgy 49 Expired
US6592872B1 Targeting antigens to the MHC class I processing pathway with an anthrax toxin fusion protein Emerging Cross-Sectional Technologies 43 Expired
US5591631A Anthrax toxin fusion proteins, nucleic acid encoding same Chemistry; Metallurgy 37 Expired
US7261900B2 Recombinant modified Bacillus anthracis protective antigen for use in vaccines Human Necessities 9 Expired
US6485925B1 Anthrax lethal factor is a MAPK kinase protease Physics 8 Expired
US7097965B2 Targeting antigens to the MHC class I processing pathway with an anthrax toxin fusion protein Emerging Cross-Sectional Technologies 5 Expired
US7947289B2 Multimeric protein toxins to target cells having multiple identifying characteristics Chemistry; Metallurgy 3 Active
US7803386B2 Poly-gamma-glutamic conjugates for eliciting immune responses directed against bacilli Human Necessities 3 Expired
US7468352B1 Mutated anthrax toxin protective antigen proteins that specifically target cells containing high amounts of cell-surface metalloproteinases or plasminogen activator receptors Chemistry; Metallurgy 2 Expired
US8388933B2 Multimeric protein toxins to target cells having multiple identifying characteristics Chemistry; Metallurgy 2 Active
US6893835B2 Anthrax lethal factor is a MAPK kinase protease Physics 2 Expired
US6911203B2 Anthrax lethal factor is a MAPK kinase protease Physics 2 Expired
US8071100B2 Monoclonal antibodies that neutralize anthrax toxins Physics 1 Active
US8961975B2 Monoclonal antibodies that neutralize anthrax toxins Physics 1 Active
US8481048B2 Methods for preparing immunogenic conjugates Human Necessities 1 Active
US9580492B2 Monoclonal antibodies that neutralize anthrax toxins Physics 1 Active
US8394387B1 Recombinant modified Bacillus anthracis protective antigen for use in vaccines Human Necessities 1 Active
US8044189B2 Bacillus anthracis protective antigen nucleic acid sequences Human Necessities 1 Active
US7763451B2 Methods for preparing Bacillus anthracis protective antigen for use in vaccines Human Necessities 1 Active
US8574853B2 Monoclonal antibodies that neutralize anthrax toxins Physics 1 Active
US8703150B2 Methods of using Bacillus anthracis protective antigen sequences for vaccination Human Necessities 1 Active
US9555064B2 Protease-deficient Bacillus anthracis Emerging Cross-Sectional Technologies 1 Active
US9730993B2 Engineered anthrax lethal toxin for targeted delivery Chemistry; Metallurgy 1 Active
US10273548B2 Protease-deficient bacillus anthracis Emerging Cross-Sectional Technologies 0 Active
US7625736B2 Methods for preparing immunogenic conjugates Human Necessities 0 Expired

Source: USPTO / EPO open patent data. Inventor disambiguation is heuristic; counts are objective bibliographic measures.