Inventor · Pacifica, CA, US

William E. Holmes

28Patents
13h-index
26Co-inventors
81Inventor score

Filing activity: Feb 25, 1974 → Jul 30, 2021

Most-cited inventions

PatentTitleAreaCited byStatus
US4816567A Recombinant immunoglobin preparations Emerging Cross-Sectional Technologies 4,524 Expired
US6331415A Methods of producing immunoglobulins, vectors and transformed host cells for use therein Emerging Cross-Sectional Technologies 578 Expired
US5367060A Structure, production and use of heregulin Human Necessities 95 Expired
US5641869A Method for purifying heregulin Human Necessities 85 Expired
US5840525A Nucleic acids, vectors and host cells encoding heregulin Human Necessities 63 Expired
US5834229A Nucleic acids vectors and host cells encoding and expressing heregulin 2-.alpha. Human Necessities 60 Expired
US7923221B1 Methods of making antibody heavy and light chains having specificity for a desired antigen Emerging Cross-Sectional Technologies 50 Expired
US5859206A Antibodies specific for heregulin 2-.alpha. Human Necessities 49 Expired
US5856110A Method of using HRG2-.alpha. to stimulate P185.sup.HeR2 Human Necessities 40 Expired
US4935237A Processes for the preparation of t-PA mutants Chemistry; Metallurgy 30 Expired
US5767063A Human IL-8 receptor and antibodies thereto Chemistry; Metallurgy 23 Expired
US6399746B1 Structure, production and use of heregulin 2 ligands Human Necessities 18 Expired
US3938089A Double read system for character recognition systems Physics 16 Expired
US5633141A Human IL-8 receptor binding assay Chemistry; Metallurgy 13 Expired
US5112755A Preparation of functional human urokinase proteins Human Necessities 12 Expired
US5783415A Method of producing an IL-8 receptor polypeptide Chemistry; Metallurgy 12 Expired
US5856457A Nucleic acids encoding a human IL-8 receptor Chemistry; Metallurgy 9 Expired
US5552284A Detection of interleukin-8 receptors by nudeic acid hybridization Chemistry; Metallurgy 9 Expired
US10485829B2 Methods of producing human RPE cells and pharmaceutical preparations of human RPE cells Chemistry; Metallurgy 8 Active
US5571702A Amplification method for detection of human PF4A receptors Chemistry; Metallurgy 8 Expired
US10077424B2 Methods of producing RPE cells and compositions of RPE cells Chemistry; Metallurgy 8 Active
US5037646A Processes for the treatment of vascular disease Chemistry; Metallurgy 5 Expired
US6953842B2 Antibodies to heregulin 2 Human Necessities 4 Expired
US7601827B2 Polynucleotides encoding polypeptides that bind to the P185HER2 receptor Human Necessities 0 Active
US11547654B2 Method of manufacture for hand-sanitizing lotion with prolonged effectiveness and resulting composition of matter Human Necessities 0 Active

Source: USPTO / EPO open patent data. Inventor disambiguation is heuristic; counts are objective bibliographic measures.