Inventor · San Diego, CA, US

Holly Hogrefe

28Patents
9h-index
23Co-inventors
75Inventor score

Filing activity: Mar 21, 1997 → Sep 11, 2023

Most-cited inventions

PatentTitleAreaCited byStatus
US8067556B2 Multi-site mutagenesis Chemistry; Metallurgy 95 Expired
US8268605B2 Compositions and methods utilizing DNA polymerases Chemistry; Metallurgy 80 Expired
US8283148B2 DNA polymerase compositions for quantitative PCR and methods thereof Chemistry; Metallurgy 62 Active
US8685676B2 Multi-site mutagenesis Chemistry; Metallurgy 59 Active
US7932070B2 High fidelity DNA polymerase compositions and uses therefor Chemistry; Metallurgy 58 Expired
US7943358B2 Polymerase enhancing factor (PEF) extracts, PEF protein complexes, isolated PEF protein, and methods for purifying and identifying Chemistry; Metallurgy 57 Active
US9783791B2 Mutant reverse transcriptase and methods of use Chemistry; Metallurgy 36 Active
US6183997A Polymerase enhancing factor (PEF) extracts PEF protein complexes isolated PEF proteins and methods for purifying and identifying same Chemistry; Metallurgy 15 Expired
US9085762B2 Compositions and methods using split polymerases Chemistry; Metallurgy 11 Active
US6803201B2 Compositions and methods for polynucleotide sequence determination Chemistry; Metallurgy 9 Expired
US6946273B1 Compositions and methods utilizing DNA polymerases Performing Operations; Transporting 8 Expired
US9523085B2 Thermostable type-A DNA polymerase mutants with increased polymerization rate and resistance to inhibitors Chemistry; Metallurgy 7 Active
US6444428B1 Polymerase enhancing factor (PEF) extracts, PEF protein complexes, isolated PEF proteins, and methods for purifying and identifying same Chemistry; Metallurgy 7 Expired
US8772006B2 Compositions and methods utilizing DNA polymerases Chemistry; Metallurgy 5 Active
US6803216B2 Compositions and methods for random nucleic acid mutagenesis Chemistry; Metallurgy 5 Expired
US6734293B1 Polymerase enhancing factor (PEF) extracts, PEF protein complexes, isolated PEF protein, and methods for purifying and identifying Chemistry; Metallurgy 3 Expired
US10240196B2 Transposase-random priming DNA sample preparation Chemistry; Metallurgy 2 Active
US7442766B2 Pfu replication accessory factors and methods of use Chemistry; Metallurgy 2 Expired
US6379553B1 Polymerase enhancing factor (PEF) extracts, PEF protein complexes, isolated PEF proteins, and methods for purifying and identifying same Chemistry; Metallurgy 2 Expired
US9181534B1 High fidelity DNA polymerase compositions and uses thereof Chemistry; Metallurgy 2 Expired
US10308979B2 Target enrichment and labeling for multi-kilobase DNA Chemistry; Metallurgy 1 Active
US9758773B2 Thermostable type-A DNA polymerase mutant with increased resistance to inhibitors in blood Chemistry; Metallurgy 1 Active
US6333165A Methods for identifying polymerase enhancing factor (PEF) Chemistry; Metallurgy 1 Expired
US7625725B1 Polymerase enhancing factor (PEF) extracts, PEF protein complexes, isolated PEF proteins, and methods for purifying and identifying them Chemistry; Metallurgy 1 Expired
USRE49207E1 Transposase-random priming DNA sample preparation General 0 Active

Source: USPTO / EPO open patent data. Inventor disambiguation is heuristic; counts are objective bibliographic measures.